Publications and Projects
Scientific Research
Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis
Magliozzi et al. show that fission yeast Pak1 regulates multiple events during cell division. Through a phosphoproteomic screen and subsequent mutant analysis, their work uncovers direct targets and mechanisms for Pak1 activity during cell growth and division.
Automated gesture tracking in head-fixed mice
Giovannucci et al. present a low-cost, easy-to-build acquisition system, along with scalable computational methods, to quantitatively measure behavior (locomotion and paws, whiskers, and tail motion patterns) in head-fixed mice locomoting on cylindrical or spherical treadmills. They benchmark their algorithms against data generated either by manual labeling or by simpler methods of feature extraction.
The Effects of Prenatal Binge-Ethanol Exposure on Pyramidal Neurons in Layer V of the Somatosensory Cortex
An undergraduate honors thesis completed at Dartmouth College. Marielle Brady (under PI Hermes Yeh) uses a mouse model to examine the distribution and morphology of pyramidal neurons following neuronal migration during development both in the presence and absence of prenatal alcohol exposure. Techniques used include cellular staining, fluorescence microscopy, and 3D modeling using Neurolucida.
Geisel School of Medicine
The Cole Lab studies the export of mRNA from the nucleus via nuclear pore complexes (NPCs). Using genetic screens and fluorescence microscopy of GFP-tagged proteins, the lab seeks to examine the construction of NPCs as well as the translocation of mRNAs from the nucleus.
Research Assistant, 2013-2015
Lab Experience
Geisel School of Medicine
Using fission yeast as a model organism, the Moseley Lab employs a wide variety of genetic, genomic, biochemical, and microscopic techniques to study the signaling pathways that connect cell growth proteins with cell cycle machinery.
Lab Technician, 2017-2019
Yeh Lab
Geisel School of Medicine
The Yeh Lab uses transgenic mouse models to study the development and plasticity of neurotransmitter-receptor interactions in the adult and developing central nervous system (CNS).
James O. Freedman Presidential Scholar, 2015-2017
Undergraduate Thesis, "The Effect of Prenatal Binge-Ethanol Exposure on Pyramidal Neurons in Layer V of the Somatosensory Cortex"
Wang Lab
Princeton Neuroscience Institute
The Wang Lab studies the function of the cerebellum beyond its role in motor function, focusing on potential involvement in learned behaviors as well as early cognitive development. The lab uses tools such as two-photon in vivo fluorescence microscopy, fast-responding calcium indicator proteins, and machine learning-based methods for tracking mouse behavior.
Princeton Neuroscience Institute Summer Internship Program, Summer 2014